Analysis of stimulus-induced brain dynamics during naturalistic paradigms

using high-resolution 7-Tesla fMRI

Faculty: Faculty of Biology

Department: Department of Neurobiology, Weizmann Institute of science

Naturalistic stimuli offer promising avenues for investigating brain function across the rich, realistic spectrum of human experiences. Functional magnetic resonance imaging (fMRI) studies of brain activity recorded during naturalistic paradigms have provided new information about dynamic neural processing in ecologically valid contexts, but the complex, uncontrolled nature of such stimuli -- and the resulting, multifaceted fMRI responses that unfold -- present challenges with respect to data analysis and interpretation.

The post-doctorate project will involve first experimental phase: conducting fMRI experiments using a newly established 7T MRI scanner during naturalistic stimulation (auditory-narratives or movies), together with recording physiological measures: pupil size, heart rate, and respiration. (ii) Developing new signal processing methods to disentangle cognitive processing from autonomic responses, and physiological “noise”, targeting memory encoding and retrieval processes.

The position is for one year starting at December 2019. Following a positive evaluation, the appointment could be extended up to 2 years.

Requirements:

Strong computational, analytical and programming skills.
Experience with fMRI and experimental work – an advantage.
Computational/engineering/physics background and programming experience.
Ability of teamwork and initiative.
Knowledge of professional English at a high level.


Details of Contact Person for Position:

The work will take place at the Lab of Dr. Ritta Schmidt (Weizmann institute of science) and will be supervised directly by Dr. Erez Simony from Holon Institute of technology (HIT).
Prof. Rafi Malach will act as an advisor to this project.

How to apply:

Interested candidates with proven academic record are requested to send their CV and contact details of 3 referees to Dr. Erez Simony (This email address is being protected from spambots. You need JavaScript enabled to view it.)

The Ben-Shaul lab at the Hebrew University Faculty of Medicine is seeking PhD students and postdoctoral fellows to join our research on chemosensory processing of social signals.
Our lab is interested in basic aspects of sensory coding as well as more ethological questions about the interplay between learned and innate behaviors.

Work in the lab involves one or more of the following approaches: electrophysiology, behavioral testing (using optogenetics), activity based gene trapping, and data analyses.
For more information, visit our website (https://yoramben-shaul.ekmd.huji.ac.il/).
Applicants should email Yoram Ben-Shaul  (This email address is being protected from spambots. You need JavaScript enabled to view it.), describing their previous experience in the field of neuroscience and their research interests.
Substantial fellowships are guaranteed to suitable and dedicated candidates.

New Position at ProteKt Therapeutics Ltd.: Senior Scientist – Neurobiology
ProteKt Therapeutics, a biotech start-up company that recently graduated the FutuRx biotech incubator, is Hiring!
Our company develops a small molecule inhibitor that targets the kinase PKR for the treatment of neurodegenerative diseases (more information can be found here)
. We seek a highly-motivated individual to join our team as a Research Scientist with the following traits:
• Ph.D. degree in neurobiology with hands-on experience
• CNS background and experience in in vitro and in vivo models of CNS diseases
• Strong experience in T.C., primary cultures of neurons, microscopy, IHC, ICC, IF staining
• Independent researcher that can plan, conduct and analyze experimental data
• Proven ability for troubleshooting and problem-solving
• A team player with great inter-personal skills that can fit in a dynamic multidisciplinary group with a common goal
• Excellent English with the ability to write scientific reports and overviews and communicate with international service providers
• Self-motivated, deadline-driven, and organized person
• Great communication skills and a positive attitude
Advantage will be given to applicant with the following background:
• Pre-clinical development and industry experience of at least two years
• Experience in leading and monitoring projects at CROs
• Experience in electrophysiology studies
• Experience with recombinant protein production and crystallography work

To apply for this job, please send your CV to: This email address is being protected from spambots. You need JavaScript enabled to view it.

למעבדה חדשה באוניברסיטת חיפה במחלקה לנוירוביולוגיה דרוש/ה מנהל/ת מעבדה.

המעבדה עוסקת במחקר של הפרעות פסיכיאטריות ומחלות נוירודגנרטיביות על-ידי תכנות מחדש של תאים שנלקחו מחולים והפיכתם לתאי גזע (( human induced pluripotent stem cells ומיונם כסוגים שונים של תאי עצב או תאי מוח אחרים.

דרישות התפקיד:

א. תואר שני או שלישי בביולוגיה או תחומים קשורים.

ב. ניסיון בשיטות עבודה מולקולריות.

ג. ניסיון בהפעלת מכשור מדעי.

ד. ניסיון בגידול תאים שונים.

למשלוח קורות חיים: This email address is being protected from spambots. You need JavaScript enabled to view it.

The Rosenblum and Stern labs are looking for a joint, highly motivated PhD student for the study of bipolar disorder using neurons derived from human patients with genomic variations that are highly associated and documented in bipolar disorder.
We have a unique and characterized cohort of patients with these genomic variants. Starting from induced pluripotent stem cells (iPSCs), the student will learn to differentiate iPSCs into hippocampal neuronal cultures and organoids. We are interested in finding disease mechanisms using electrophysiology (such as imaging of calcium transients and whole cell patch clamp) and molecular biology for better understanding of the disease and with the goal of improving treatment.
Applicants are invited to send their CV and the names of 2 referees to This email address is being protected from spambots. You need JavaScript enabled to view it. or This email address is being protected from spambots. You need JavaScript enabled to view it.  

Postdoc position is available in the laboratory of Dr. Anders Buonnano, National Institute of Child Health and Human Development, in the field of neuroscience.

For more information please click here.

דרוש/ה מנהל/ת מעבדה – מהנדס/ת מעבדה

לעבודה במעבדת מחקר במחלקה לפיזיולויגה וביולוגיה של התא, הפקולטה למדעי הבריאות, אוניברסיטת בן גוריון בנגב.

דרישות התפקיד:

א. תואר שני במדעי החיים/ ביוטכנולוגיה/ביוכימיה/ ביולוגיה.

ב. ניסיון של 5 שנים בתחומים רלוונטיים.

ג. ניסיון בשיטות עבודה מולקולריות.

ד. ניסיון בהפעלת מכשור מדעי.

המשרה כוללת 50% משרה באוניברסיטת בן גוריון + 50% ממענקי מחקר

לפרטים:

חוה גולן This email address is being protected from spambots. You need JavaScript enabled to view it.

איתי רוסו This email address is being protected from spambots. You need JavaScript enabled to view it.

הגשת מועמדות תיעשה דרך אתר האוניברסיטה בלבד. יש להיכנס לקישור הבא: http://in.bgu.ac.il/hr/Pages/Wanted.aspx

We are seeking a highly motivated postdoctoral fellow to carry out a research project aiming to study molecular mechanisms of memory formation and enhancement. Toward that end, the successful applicant will utilize state-of-the-art molecular and cellular techniques and behavioral approaches including optogenetic (e.g. Alapin et al., Cell Reports, 2018). 

Basic qualifications 

- A recent PhD degree in neuroscience, molecular/cell biology or related fields. 

- Experience in the following areas is desired: Optogenetic, in vivo electrophysiology/miniature microscope, imaging of dendritic spines, mouse behavior. 

- High level of motivation and independence and the ability to think critically are expected. Candidates must have good written/oral communication skills in English. 

An application package, including a motivation letter, curriculum vitae, list of publications and names of 2-3 referees, should be sent to This email address is being protected from spambots. You need JavaScript enabled to view it.

Website: https://rafilamprecht.wixsite.com/laboratorymemory